Routemap and Useful Links
Through the use of an interactive routemap, the National Insitute for Research website provides information on best practice and outlines the current legal and practical requirements for conducting clinical trials. Click here to view the Interactive Routemap.
National Institute for Health Research: The NIHR commissions and fund NHS, social care and public health research that is essential for delivering our responsibilities in public, health and personal social services. Our role is to develop the research evidence to support decision making by professionals, policy makers and patients, make this evidence available, and encourage its uptake and use. Click here for more information.
Peninsula Clinical Trials Unit: The Peninsula Clinical Trials Unit (PenCTU) is a UK Clinical Research Collaboration (UKCRC) Registered Clinical Trials Unit, currently supported by a NIHR CTU infrastructure grant. The PenCTU has expertise in developing, supporting and coordinating multi-centre clinical trials and other well-designed studies, and works with research networks and key partners to deliver the full spectrum of clinical trial expertise across the South West Peninsula. Click here for more information.
The Plymouth Lymphoma Trials Unit (PLTU): Our aim is increasing public and professional knowledge of mantle cell lymphoma: its diagnosis, treatment options (especially possibly clinical trials) and prognosis. Click here for more information.
Research Design Service South West: The RDS exists to provide help for people preparing research proposals for submissions to peer reviewed funding competitions for applied health or social care research. Click here for more information.
EQUATOR Network: The EQUATOR Network works to improve the reliability and value of medical research literature by promoting transparent and accurate reporting of research studies. Click here for more information.
PenCLAHRC: The National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) for the South West Peninsula - or PenCLAHRC - undertakes high-quality applied health research focused on the needs of patients and support the translation of research evidence into practice in the NHS. Click here for more information.
MHRA: Before a medicine can be authorised for use, it must go through the clinical trials process to ensure that it is safe and effective and also that the quality of the product is sufficient. This section contains information on every aspect of the clinical trials process. Click here for more information.
ICH: Lots of useful guidance regarding clinical trials. Includes the ICH GCP E6 Guidance document. Click here for more information.
HTA: With the interests of the public and those we regulate at the centre of our work, we aim to maintain confidence by ensuring that human tissue is used safely and ethically, and with proper consent. We regulate organisations that remove, store and use tissue for research, medical treatment, post-mortem examination, teaching and display in public. We also give approval for organ and bone marrow donations from living people. Click here for more information.
MRC: The Hubs for Trials Methodology Research (HTMR) were established by the MRC to create a UK-wide regionally distributed research resource to improve the design, conduct, analysis, interpretation, and reporting of clinical trials. Click here for more information.
Bandolier: An independent journal about evidence-based healthcare. Click here for more information.
EU commission (EudraLex - Volume 10 Clinical trials guidelines): Volume 10 of the publications "The rules governing medicinal products in the European Union" contains guidance documents applying to clinical trials. Click here for more information.
Improving Medical Statistics and the Intrepretation of Clinical Trials: There is considerable variability in the information that the public and physicians receive regarding the results of medical trials. One contributing factor is the incorrect application of statistics in the medical literature. A more common source of error is that the conclusions of a study are not always a reasonable reflection of the data presented.The site includes examples of the misuse of statistics and inappropriate conclusions in the medical literature. Some suggestions for improvement are also suggested. Click here for more information.
Statistics for the terrified: The items available from this page are provided free to anyone who is struggling to understand statistical concepts. We regularly add items here, so please contact us if there is a topic you would like us to cover. Click here for more information.
NHS Health Research Authority: National Research Ethics Service; protecting the rights, safety, dignity and well-being of research participants. Facilitating and promoting ethical research that is of potential benefit to participants, science and society. Click here for more information.
PubMed: Searchable database for research. Click here for more information.
Amedeo: Searchable database for research, papers available free online. Click here for more information.
South West Anaesthesia Research Matrix (SWARM): Click here for more information.
UK Clinical Trials Gateway: The UK Clinical Trials Gateway (UKCTG) is aimed at patients and medics to allow them to search a number of different international trial registries to find clinical trials that are of interest to them that are taking place in the United Kingdom. Click here for more information.
Health Research Authority (HRA): The HRA was established in December 2011 to protect and promote the interests of patients and the public in health research, and to streamline the regulation of research. Through the streamlining, ethical review and approval of health research, we help to build both public confidence and participation in health research, and so improve the nation’s health. Click here for more information.
Number needed to treat (NNT): If you are ever asked to calculate the Number Needed to Treat this little free app may be just the thing (Graph Pad, 2013). Click here for more information.
Clinical Practice Research Datalink: The CPRD is a key part of the government’s Plan for Growth and will enable health researchers to have better access to anonymised NHS data from patients suffering with different health conditions like cancer and diabetes. Click here for more information.
Clinical Trial Magnifier: This is a useful website providing lots of helpful and free advise for Clinical Research Professionals. Click here for more information.