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- C: Call for Concern (Martha's Rule)
- C: Cancer Education Hub
- C: Cancer Services
- C: Cardiology
- C: Cardiothoracic Surgery
- C: Cellular and Anatomical Pathology
- C: Chemotherapy Unit
- C: Chest Clinic
- C: Child Development Centre
- C: Children's Theatres
- C: Children’s Psychological Health and Wellbeing
- C: Clinical Engineering
- C: Clinical Psychology
- C: Colorectal
- C: Colposcopy
- C: Complications of Excess Weight (CEW) Service
- C: Covid rehabilitation
- C: Cytopathology
- C: Derriford Children's Cancer Service (DCCS)
- C: Derriford Combined Laboratory
- C: Paediatrics
- C: Pastoral & Spiritual Care (Chaplaincy)